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CREB3L2 / BBF2H7 Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - CREB3L2 / BBF2H7 Antibody (internal region) AF3078a
    AF3078a (1 µg/ml) staining of Rat Testis lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q70SY1
Other Accession NP_919047.2, 64764, 208647 (mouse), 362339 (rat)
Reactivity Mouse, Rat
Predicted Human, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 57415 Da
Additional Information
Gene ID 64764
Other Names Cyclic AMP-responsive element-binding protein 3-like protein 2, cAMP-responsive element-binding protein 3-like protein 2, BBF2 human homolog on chromosome 7, Processed cyclic AMP-responsive element-binding protein 3-like protein 2, CREB3L2, BBF2H7
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCREB3L2 / BBF2H7 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CREB3L2
Synonyms BBF2H7
Function Transcriptional activator which is processed and activated during endoplasmic reticulum stress late phase. Binds to the cAMP response element (CRE) and activates transcription through CRE. Regulates the transcription of unfolded protein response target genes, preventing accumulation of unfolded proteins in damaged neurons. Also regulates the expression of SEC23A, accelerating protein trafficking from the ER to the Golgi thereby playing a key role in chondrocyte differentiation and formation of epiphyseal cartilage (By similarity).
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein
Tissue Location Widely expressed with highest levels in placenta, lung, spleen and intestine, and lowest levels in heart, brain, skeletal muscle, thymus, colon and leukocytes. In fetal tissues, the weakest expression is detected in brain and heart
Research Areas
Citations (0)

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Characterization of the human CREB3L2 gene promoter. Panagopoulos I, Mertens F, Oncology reports 2009 Mar 21 (3): 615-24. PMID: 19212619

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$ 325.00
Cat# AF3078a
(40 western blots)
Availability: 7-10 days
Bulk Size
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