|Other Accession||NP_653305.1, NP_001018070.1, NP_001139760.1, 150209, 72168 (mouse), 303786 (rat)|
|Predicted||Human, Mouse, Rat, Dog, Cow|
|Calculated MW||66791 Da|
|Other Names||Apoptosis-inducing factor 3, 1.-.-.-, Apoptosis-inducing factor-like protein, AIFM3, AIFL|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AIFM3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.|
|Cellular Location||Mitochondrion. Note=Does not translocate to the nucleus upon induction of apoptosis|
|Tissue Location||Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize all isoforms (NP_653305.1; NP_001018070.1, NP_001139760.1).
H. pylori-induced apoptosis in human gastric cancer cells mediated via the release of apoptosis-inducing factor from mitochondria. Ashktorab H, Dashwood RH, Dashwood MM, Zaidi SI, Hewitt SM, Green WR, Lee EL, Daremipouran M, Nouraie M, Malekzadeh R, Smoot DT. Helicobacter 2008 Dec 13 (6): 506-17. PMID: 19166416
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