|Application ||IHC, E|
|Other Accession||NP_001037.1, 6558, 20496 (mouse), 83629 (rat)|
|Predicted||Mouse, Rat, Dog, Cow|
|Calculated MW||131447 Da|
|Other Names||Solute carrier family 12 member 2, Basolateral Na-K-Cl symporter, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1, SLC12A2, NKCC1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC12A2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in many tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Analysis of gene polymorphisms associated with K ion circulation in the inner ear of patients susceptible and resistant to noise-induced hearing loss. Pawelczyk M, Van Laer L, Fransen E, Rajkowska E, Konings A, Carlsson PI, Borg E, Van Camp G, Sliwinska-Kowalska M, Annals of human genetics 2009 Jul 73 (Pt 4): 411-21. PMID: 19523148
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