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PAX4 Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - PAX4 Antibody (internal region) AF3081a
    AF3081a (0.2 µg/ml) staining of Mouse Pancreas lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • EIA - PAX4 Antibody (internal region) AF3081a
    EB9787 (1.5ug/ml) as the reporter with EB002021 as the capture rabbit antibody (5ug/ml).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43316
Other Accession NP_006184.2, 5078, 18506 (mouse), 83630 (rat)
Reactivity Human, Mouse
Predicted Rat, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 37833 Da
Additional Information
Gene ID 5078
Other Names Paired box protein Pax-4, PAX4
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPAX4 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PAX4
Function Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.
Cellular Location Nucleus.
Research Areas
Citations (0)

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A-beta-subtype of ketosis-prone diabetes is not predominantly a monogenic diabetic syndrome. Haaland WC, Scaduto DI, Maldonado MR, Mansouri DL, Nalini R, Iyer D, Patel S, Guthikonda A, Hampe CS, Balasubramanyam A, Metzker ML, Diabetes care 2009 May 32 (5): 873-7. PMID: 19228875

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$ 325.00
Cat# AF3081a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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