|Other Accession||NP_055332.3, NP_001121632.1, 7342, 22221 (mouse), 301038 (rat)|
|Predicted||Human, Mouse, Rat, Dog|
|Calculated MW||60491 Da|
|Other Names||Upstream-binding protein 1, Transcription factor LBP-1, UBP1, LBP1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||UBP1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.|
|Tissue Location||Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Reported variants represent identical protein: NP_001121633.1, NP_055332.3.
LBP-1b, LBP-9, and LBP-32/MGR detected in syncytiotrophoblasts from first-trimester human placental tissue and their transcriptional regulation. Henderson YC, Frederick MJ, Wang MT, Hollier LM, Clayman GL, DNA and cell biology 2008 Feb 27 (2): 71-9. PMID: 18004979
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.