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TPPP/p25 Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - TPPP/p25 Antibody (internal region) AF3088a
    AF3088a (0.001 µg/ml) staining of Human Cerebellum lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • IHC - TPPP/p25 Antibody (internal region) AF3088a
    AF3088a (3.8 µg/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O94811
Other Accession NP_008961.1, 11076, 72948 (mouse), 361466 (rat)
Reactivity Human, Mouse, Rat
Predicted Pig
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 23694 Da
Additional Information
Gene ID 11076
Other Names Tubulin polymerization-promoting protein, TPPP, 25 kDa brain-specific protein, TPPP/p25, p24, p25-alpha, TPPP, TPPP1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTPPP/p25 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TPPP1
Function May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Note=Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies
Tissue Location Widely expressed.
Research Areas
Citations (0)

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An unstructured protein with destructive potential: TPPP/p25 in neurodegeneration. Ovádi J, Orosz F. BioEssays : news and reviews in molecular, cellular and developmental biology 2009 Jun 31 (6): 676-86. PMID: 19382230

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$ 325.00
Cat# AF3088a
(40 western blots)
Availability: 7-10 days
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