|Application ||WB, IHC, E|
|Other Accession||NP_008961.1, 11076, 72948 (mouse), 361466 (rat)|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||23694 Da|
|Other Names||Tubulin polymerization-promoting protein, TPPP, 25 kDa brain-specific protein, TPPP/p25, p24, p25-alpha, TPPP, TPPP1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TPPP/p25 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Note=Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
An unstructured protein with destructive potential: TPPP/p25 in neurodegeneration. Ovádi J, Orosz F. BioEssays : news and reviews in molecular, cellular and developmental biology 2009 Jun 31 (6): 676-86. PMID: 19382230
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