PDE1A Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P54750 |
Other Accession | NP_005010.2, 5136, 18573 (mouse), 81529 (rat) |
Reactivity | Human |
Predicted | Mouse, Rat, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 61252 Da |
Gene ID | 5136 |
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Other Names | Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1A, Cam-PDE 1A, 3.1.4.17, 61 kDa Cam-PDE, hCam-1, PDE1A |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PDE1A Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PDE1A (HGNC:8774) |
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Function | Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. |
Tissue Location | Several tissues, including brain, kidney, testes and heart |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize isoform 1 (NP_005010.2) only.
References
Association study of phosphodiesterase genes in the Sequenced Treatment Alternatives to Relieve Depression sample. Cabanero M, Laje G, Detera-Wadleigh S, McMahon FJ, Pharmacogenetics and genomics 2009 Mar 19 (3): 235-8. PMID: 19214142
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