|Application ||WB, E|
|Other Accession||NP_005483.1, 10047|
|Calculated MW||16275 Da|
|Other Names||Cystatin-8, Cystatin-related epididymal spermatogenic protein, CST8, CRES|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Cystatin 8 (aa 23-34) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Performs a specialized role during sperm development and maturation.|
|Tissue Location||Proximal caput region of the epididymis. Lower expression in the testis. Within the testis it is localized to the elongating spermatids, whereas within the epididymis it is exclusively synthesized by the proximal caput epithelium|
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Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. Chapuis J, Hot D, Hansmannel F, Kerdraon O, Ferreira S, Hubans C, Maurage CA, Huot L, Bensemain F, Laumet G, Ayral AM, Fievet N, Hauw JJ, DeKosky ST, Lemoine Y, Iwatsubo T, Wavrant-DevriÃ¨ze F, Dartigues JF, Tzourio C, BuÃ©e L, Pasquier F, Berr C, Mann D, Molecular psychiatry 2009 Nov 14 (11): 1004-16. PMID: 19204726
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