|Application ||IHC, E|
|Other Accession||NP_055455.3, 9654, 67534 (mouse), 690512 (rat)|
|Predicted||Mouse, Rat, Cow|
|Calculated MW||133378 Da|
|Other Names||Tubulin polyglutamylase TTLL4, 6.-.-.-, Tubulin--tyrosine ligase-like protein 4, TTLL4, KIAA0173|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TTLL4 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Polyglutamylase which preferentially modifies beta- tubulin and nucleosome assembly proteins NAP1 and NAP2. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity).|
|Cellular Location||Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body Note=Located in cilia. In some cells, also found in basal bodies (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Characterization of the human tubulin tyrosine ligase-like 1 gene (TTLL1) mapping to 22q13.1. Trichet V, Ruault M, RoizÃ¨s G, De Sario A, Gene 2000 Oct 257 (1): 109-17. PMID: 11054573
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