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MMP12 Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - MMP12 Antibody (internal region) AF3117a
    AF3117a (0.5 µg/ml) staining of Human Breast Cancer lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P39900
Other Accession NP_002417.2, 4321
Reactivity Human
Predicted Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 54002 Da
Additional Information
Gene ID 4321
Other Names Macrophage metalloelastase, MME,, Macrophage elastase, ME, hME, Matrix metalloproteinase-12, MMP-12, MMP12, HME
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMMP12 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MMP12
Synonyms HME
Function May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Found in alveolar macrophages but not in peripheral blood monocytes
Research Areas
Citations (0)

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Association of MMP1, MMP3, MMP9, and MMP12 polymorphisms with risk and clinical course of multiple sclerosis in a Polish population. Mirowska-Guzel D, Gromadzka G, Czlonkowski A, Czlonkowska A, Journal of neuroimmunology 2009 Sep 214 (1-2): 113-7. PMID: 19628284

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$ 325.00
Cat# AF3117a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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