|Application ||WB, IHC, IF, E|
|Other Accession||NP_005262.1, NP_036216.2, 2746, 2747, 14661 (mouse), 24399 (rat)|
|Predicted||Rat, Dog, Cow|
|Calculated MW||61398 Da|
|Other Names||Glutamate dehydrogenase 1, mitochondrial, GDH 1, 22.214.171.124, GLUD1, GLUD|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Glutamate Dehydrogenase Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).|
|Cellular Location||Mitochondrion matrix.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_005262.1; NP_036216.2).
Expression of enzymes regulating
placental ammonia homeostasis in human fetal growth restricted pregnancies. Jozwik M, Pietrzycki B, Jozwik M, Anthony RV. Placenta. 2009 Jul;30(7):607-12. PMID: 19500843
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