|Application ||WB, E|
|Other Accession||NP_000009.1, NP_001029031.1, 37|
|Calculated MW||70390 Da|
|Other Names||Very long-chain specific acyl-CoA dehydrogenase, mitochondrial, VLCAD, 220.127.116.11, ACADVL, VLCAD|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VLCAD Antibody (C-Term, near) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons.|
|Cellular Location||Mitochondrion inner membrane.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_000009.1; NP_001029031.1).
basis for correction of very-long-chain acyl-coenzyme A dehydrogenase deficiency by bezafibrate in patient fibroblasts: toward a genotype-based therapy. Gobin-Limballe S, Djouadi F, Aubey F, Olpin S, Andresen BS, Yamaguchi S,
Mandel H, Fukao T, Ruiter JP, Wanders RJ, McAndrew R, Kim JJ, Bastin J. Am J Hum Genet. 2007 Dec;81(6):1133-43. PMID: 17999356
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