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HSH2D Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - HSH2D Antibody (internal region) AF3145a
    AF3145a (0.3 µg/ml) staining of K562 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96JZ2
Other Accession NP_116244.1, 84941, 209488 (mouse)
Reactivity Human
Predicted Mouse
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 39002 Da
Additional Information
Gene ID 84941
Other Names Hematopoietic SH2 domain-containing protein, Hematopoietic SH2 protein, Adaptor in lymphocytes of unknown function X, HSH2D, ALX
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHSH2D Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HSH2D
Synonyms ALX
Function May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter.
Cellular Location Cytoplasm. Nucleus.
Tissue Location Predominantly expressed in spleen and hematopoietic cells such as peripheral blood leukocytes and weakly expressed in prostate, thymus, heart, small intestine and placenta.
Research Areas
Citations (0)

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The carboxyl-terminal segment of the adaptor protein ALX directs its nuclear export during T cell activation. Shapiro MJ, Chen YY, Shapiro VS, The Journal of biological chemistry 2005 Nov 280 (46): 38242-6. PMID: 16169852

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$ 325.00
Cat# AF3145a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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