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TRIM71 (aa390-402) Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - TRIM71 (aa390-402) Antibody (internal region) AF3147a
    AF3147a (0.5 µg/ml) staining of HEK293 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q2Q1W2
Other Accession NP_001034200.1, 131405, 636331 (mouse), 301042 (rat)
Reactivity Human, Mouse
Predicted Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 93385 Da
Additional Information
Gene ID 131405
Other Names E3 ubiquitin-protein ligase TRIM71, 6.3.2.-, Protein lin-41 homolog, Tripartite motif-containing protein 71, TRIM71, LIN41
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTRIM71 (aa390-402) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRIM71
Synonyms LIN41
Function E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1 (By similarity).
Cellular Location Cytoplasm, P-body.
Tissue Location Specifically expressed in testis.
Research Areas
Citations (0)

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Human TRIM71 and its nematode homologue are targets of let-7 microRNA and its zebrafish orthologue is essential for development. Lin YC, Hsieh LC, Kuo MW, Yu J, Kuo HH, Lo WL, Lin RJ, Yu AL, Li WH, Molecular biology and evolution 2007 Nov 24 (11): 2525-34. PMID: 17890240

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$ 325.00
Cat# AF3147a
(40 western blots)
Availability: 7-10 days
Bulk Size
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