|Application ||WB, E|
|Other Accession||NP_004357.3, 1181, 12724 (mouse), 29232 (rat)|
|Predicted||Mouse, Rat, Rabbit, Dog, Cow|
|Calculated MW||98535 Da|
|Other Names||Chloride channel protein 2, ClC-2, CLCN2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CLCN2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Ubiquitously expressed. Moderately expressed in aortic and coronary vascular smooth muscle cells and expressed at a low level in aortic endothelial cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize all reported isoforms (NP_004357.3; NP_001164558.1; NP_001164559.1; NP_001164560.1).
Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: role of a tyrosine endocytosis motif in surface retrieval. Cornejo I, Niemeyer MI, Zúñiga L, Yusef YR, Sepúlveda FV, Cid LP. J Cell Physiol. 2009 Dec;221(3):650-7. PMID: 19711355
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