POU3F2 / BRN2 / OCT7 Antibody (internal region, near N-Term)
Peptide-affinity purified goat antibody
|Application ||WB, E|
|Other Accession||NP_005595.2, 5454, 18992 (mouse), 29588 (rat)|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||46893 Da|
|Other Names||POU domain, class 3, transcription factor 2, Brain-specific homeobox/POU domain protein 2, Brain-2, Brn-2, Nervous system-specific octamer-binding transcription factor N-Oct-3, Octamer-binding protein 7, Oct-7, Octamer-binding transcription factor 7, OTF-7, POU3F2, BRN2, OCT7, OTF7|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||POU3F2 / BRN2 / OCT7 Antibody (internal region, near N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BRN2, OCT7, OTF7|
|Function||Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters (By similarity).|
|Tissue Location||Expressed specifically in the neuroectodermal cell lineage|
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Provided below are standard protocols that you may find useful for product applications.
Expression and purification of human full-length N Oct-3, a transcription factor involved in melanoma growth. Cabos-Siguier B, Steunou AL, Joseph G, Alazard R, Ducoux-Petit M, Nieto L, Monsarrat B, Erard M, Clottes E, Protein expression and purification 2009 Mar 64 (1): 39-46. PMID: 18996486
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