|Application ||WB, E|
|Other Accession||NP_002693.3, 5463|
|Predicted||Rat, Dog, Cow|
|Calculated MW||32645 Da|
|Other Names||POU domain, class 6, transcription factor 1, Brain-specific homeobox/POU domain protein 5, Brain-5, Brn-5, mPOU homeobox protein, POU6F1, BRN5, MPOU, TCFB1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||POU6F1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BRN5, MPOU, TCFB1|
|Function||Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3').|
|Tissue Location||In the embryo, expressed exclusively in the developing brain, whereas in the adult its expression is restricted to brain, heart, skeletal muscle and lung. In the brain, the highest expression levels are found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum|
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Provided below are standard protocols that you may find useful for product applications.
Structure of human Brn-5 transcription factor in complex with CRH gene promoter. Pereira JH, Kim SH, Journal of structural biology 2009 Aug 167 (2): 159-65. PMID: 19450691
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