HOXA9 (aa49-60) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P31269 |
Other Accession | NP_689952.1, 3205 |
Reactivity | Mouse |
Predicted | Human, Rat, Dog, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 30172 Da |
Gene ID | 3205 |
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Other Names | Homeobox protein Hox-A9, Homeobox protein Hox-1G, HOXA9, HOX1G |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HOXA9 (aa49-60) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HOXA9 |
---|---|
Synonyms | HOX1G |
Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of SELE/E-selectin and VCAM1 on the endothelial cells surface at sites of inflammation (PubMed:22269951). Positively regulates EIF4E- mediated mRNA nuclear export and also increases the translation efficiency of ODC mRNA in the cytoplasm by competing with factors which repress EIF4E activity such as PRH (By similarity). |
Cellular Location | Nucleus. Cytoplasm |
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Provided below are standard protocols that you may find useful for product applications.
References
HOXA9 modulates its oncogenic partner Meis1 to influence normal hematopoiesis. Hu YL, Fong S, Ferrell C, Largman C, Shen WF, Molecular and cellular biology 2009 Sep 29 (18): 5181-92. PMID: 19620287
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