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RDH5 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q92781 |
| Other Accession | NP_002896.2, 5959, 366791 (rat) |
| Predicted | Human, Rat, Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 34979 Da |
| Gene ID | 5959 |
|---|---|
| Other Names | 11-cis retinol dehydrogenase, 11-cis RDH, 11-cis RoDH, 1.1.1.315, 9-cis retinol dehydrogenase, 9cRDH, RDH5, RDH1 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RDH5 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RDH5 (HGNC:9940) |
|---|---|
| Function | Catalyzes the oxidation of cis-isomers of retinol, including 11-cis-, 9-cis-, and 13-cis-retinol in an NAD-dependent manner (PubMed:11675386, PubMed:10588954, PubMed:9931293, PubMed:9115228). Has no activity towards all-trans retinal (By similarity). Plays a significant role in 11-cis retinol oxidation in the retinal pigment epithelium cells (RPE). Also recognizes steroids (androsterone, androstanediol) as its substrates (PubMed:9931293, PubMed:29541409). |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein; Lumenal side |
| Tissue Location | Widely expressed. In the eye, abundant in the retinal pigment epithelium. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jörnvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U, Chemico-biological interactions 2009 Mar 178 (1-3): 94-8. PMID: 19027726
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