|Application ||WB, IHC, E|
|Other Accession||NP_000682.3, 218|
|Calculated MW||50395 Da|
|Other Names||Aldehyde dehydrogenase, dimeric NADP-preferring, 188.8.131.52, ALDHIII, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase family 3 member A1, ALDH3A1, ALDH3|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ALDH3A1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.|
|Tissue Location||High levels in stomach, esophagus and lung; low level in the liver and kidney|
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Provided below are standard protocols that you may find useful for product applications.
Reported variants represent identical protein: NP_001128639.1, NP_000682.3, NP_001128640.1
The oxidation status of ALDH3A1 in human saliva and its correlation with antioxidant capacity measured by ORAC method. Bogucka M, Giebu?towicz J, Zawada K, Wroczy?ski P, Wierzchowski J, Pietrzak M, Piekarczyk P, Romanowska K. Acta poloniae pharmaceutica 66 (5): 477-82. PMID: 19894643
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