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ALDH3A1 Antibody (C-Term)

Peptide-affinity purified goat antibody

     
  • WB - ALDH3A1 Antibody (C-Term) AF3239a
    AF3239a (0.01 µg/ml) staining of Mouse Eye lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • IHC - ALDH3A1 Antibody (C-Term) AF3239a
    AF3239a (3.8 µg/ml) staining of paraffin embedded Human Lung. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession P30838
Other Accession NP_000682.3, 218
Reactivity Human, Mouse
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 50395 Da
Additional Information
Gene ID 218
Other Names Aldehyde dehydrogenase, dimeric NADP-preferring, 1.2.1.5, ALDHIII, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase family 3 member A1, ALDH3A1, ALDH3
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsALDH3A1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ALDH3A1
Synonyms ALDH3
Function ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (PubMed:1737758). Preferentially oxidizes aromatic aldehyde substrates (PubMed:1737758). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:P47739}.
Tissue Location High levels in stomach, esophagus and lung; low level in the liver and kidney
Research Areas
Citations (0)

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Background

Reported variants represent identical protein: NP_001128639.1, NP_000682.3, NP_001128640.1

References

The oxidation status of ALDH3A1 in human saliva and its correlation with antioxidant capacity measured by ORAC method. Bogucka M, Giebu?towicz J, Zawada K, Wroczy?ski P, Wierzchowski J, Pietrzak M, Piekarczyk P, Romanowska K. Acta poloniae pharmaceutica 66 (5): 477-82. PMID: 19894643

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$ 335.00
Cat# AF3239a
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