|Application ||WB, E|
|Other Accession||NP_000685.1, 221|
|Predicted||Mouse, Rat, Dog, Cow|
|Calculated MW||51840 Da|
|Other Names||Aldehyde dehydrogenase family 3 member B1, 220.127.116.11, Aldehyde dehydrogenase 7, ALDH3B1, ALDH7|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ALDH3B1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation.|
|Cellular Location||Cell membrane; Lipid-anchor. Note=Primarily in the plasma membrane as well as in some punctate structures in the cytoplasm|
|Tissue Location||Highest expression in kidney and lung.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize isoform a (NP_000685.1) only. This antibody is not expected to cross react with ALDH3B2. Reported variants represent identical protein: NP_000685.1, NP_001154945.1
Evidence of epistasis between the catechol-O-methyltransferase and aldehyde dehydrogenase 3B1 genes in paranoid schizophrenia. Wang Y, Hu Y, Fang Y, Zhang K, Yang H, Ma J, Xu Q, Shen Y, Biological psychiatry 2009 Jun 65 (12): 1048-54. PMID: 19159868
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