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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Goat Antibodies   >   Desmoplakin (aa 1546-1558) Antibody (internal region)   

Desmoplakin (aa 1546-1558) Antibody (internal region)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P15924
Other Accession NP_004406.2, 1832, 109620 (mouse), 306871 (rat)
Predicted Human, Mouse, Rat, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 331774 Da
Additional Information
Gene ID 1832
Other Names Desmoplakin, DP, 250/210 kDa paraneoplastic pemphigus antigen, DSP
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDesmoplakin (aa 1546-1558) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DSP
Function Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin- plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.
Cellular Location Cell junction, desmosome. Cytoplasm, cytoskeleton. Note=Innermost portion of the desmosomal plaque. Colocalizes with epidermal KRT5-KRT14 and simple KRT8-KRT18 keratins and VIM intermediate filaments network
Tissue Location Isoform DPI is apparently an obligate constituent of all desmosomes. Isoform DPII resides predominantly in tissues and cells of stratified origin
Research Areas
Citations (0)

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This antibody is expected to recognize reported isoform I (NP_004406.2) only.


Role of genetic testing in arrhythmogenic right ventricular cardiomyopathy/dysplasia. Barahona-Dussault C, Benito B, Campuzano O, Iglesias A, Leung TL, Robb L, Talajic M, Brugada R, Clinical genetics 2010 Jan 77 (1): 37-48. PMID: 19863551

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$ 325.00
Cat# AF3250a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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