|Application ||WB, E|
|Other Accession||NP_065134.1, 57122, 103468 (mouse), 116555 (rat)|
|Predicted||Rat, Dog, Cow|
|Calculated MW||106374 Da|
|Other Names||Nuclear pore complex protein Nup107, 107 kDa nucleoporin, Nucleoporin Nup107, NUP107|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NUP107 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC.|
|Cellular Location||Nucleus membrane Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Note=Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). Dissociates from the dissasembled NPC structure late during prophase of mitosis (PubMed:11564755)|
|Tissue Location||Ubiquitously expressed in fetal and adult tissues.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Architectural nucleoporins Nup157/170 and Nup133 are structurally related and descend from a second ancestral element. Whittle JR, Schwartz TU, The Journal of biological chemistry 2009 Oct 284 (41): 28442-52. PMID: 19674973
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