|Application ||WB, E|
|Other Accession||NP_065134.1, 57122, 103468 (mouse), 116555 (rat)|
|Predicted||Rat, Dog, Cow|
|Calculated MW||106374 Da|
|Other Names||Nuclear pore complex protein Nup107, 107 kDa nucleoporin, Nucleoporin Nup107, NUP107|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NUP107 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC.|
|Cellular Location||Nucleus membrane Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Note=Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). Dissociates from the dissasembled NPC structure late during prophase of mitosis (PubMed:11564755)|
|Tissue Location||Ubiquitously expressed in fetal and adult tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Architectural nucleoporins Nup157/170 and Nup133 are structurally related and descend from a second ancestral element. Whittle JR, Schwartz TU, The Journal of biological chemistry 2009 Oct 284 (41): 28442-52. PMID: 19674973
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