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DNAH11 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q96DT5 |
| Other Accession | NP_003768.2, 8701, 13411 (mouse) |
| Predicted | Human, Mouse, Dog, Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 520369 Da |
| Gene ID | 8701 |
|---|---|
| Other Names | Dynein heavy chain 11, axonemal, Axonemal beta dynein heavy chain 11, Ciliary dynein heavy chain 11, DNAH11 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DNAH11 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DNAH11 (HGNC:2942) |
|---|---|
| Function | Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. |
| Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme Note=Located in the proximal region of respiratory cilia |
| Tissue Location | Expressed in airway ciliated epithelial cells (at protein level) (PubMed:31178125, PubMed:33139725). Not detected in spermatozoa (at protein level) (PubMed:31178125) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Ciliary defects and genetics of primary ciliary dyskinesia. Escudier E, Duquesnoy P, Papon JF, Amselem S, Paediatric respiratory reviews 2009 Jun 10 (2): 51-4. PMID: 19410201
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