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GRM2 Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - GRM2 Antibody (internal region) AF3274a
    AF3274a (1 µg/ml) staining of Human Hippocampus lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • IHC - GRM2 Antibody (internal region) AF3274a
    AF3274a (3.8 µg/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14416
Other Accession NP_000830.2, NP_001123535.1, 2912, 108068 (mouse), 24415 (rat)
Reactivity Human
Predicted Mouse, Rat, Rabbit, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 95568 Da
Additional Information
Gene ID 2912
Other Names Metabotropic glutamate receptor 2, mGluR2, GRM2, GPRC1B, MGLUR2
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGRM2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRM2
Synonyms GPRC1B, MGLUR2
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite
Tissue Location Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain.
Research Areas
Citations (0)

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This antibody is expected to recognize both isoforms (NP_000830.2; NP_001123535.1).


Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population. So HC, Fong PY, Chen RY, Hui TC, Ng MY, Cherny SS, Mak WW, Cheung EF, Chan RC, Chen EY, Li T, Sham PC, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010 Jan 153B (1): 103-13. PMID: 19367581

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$ 325.00
Cat# AF3274a
(40 western blots)
Availability: 7-10 days
Bulk Size
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