ARHGDIG Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q99819 |
Other Accession | NP_001167.2, 398, 14570 (mouse), 360500 (rat) |
Reactivity | Human |
Predicted | Mouse, Rat, Dog, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 25098 Da |
Gene ID | 398 |
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Other Names | Rho GDP-dissociation inhibitor 3, Rho GDI 3, Rho-GDI gamma, ARHGDIG |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ARHGDIG Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ARHGDIG |
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Function | Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP. |
Cellular Location | Cytoplasm. |
Tissue Location | Primarily expressed in pancreas and brain. |
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Provided below are standard protocols that you may find useful for product applications.
References
Application of gene network analysis techniques identifies AXIN1/PDIA2 and endoglin haplotypes associated with bicuspid aortic valve. Wooten EC, Iyer LK, Montefusco MC, Hedgepeth AK, Payne DD, Kapur NK, Housman DE, Mendelsohn ME, Huggins GS, PloS one 2010 5 (1): e8830. PMID: 20098615
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