|Other Accession||NP_060482.2, 55083, 269152 (mouse), 305012 (rat)|
|Predicted||Human, Mouse, Rat, Dog, Cow|
|Calculated MW||223883 Da|
|Other Names||Kinesin-like protein KIF26B, KIF26B|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KIF26B Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Although it seems to lack ATPase activity it is constitutively associated with microtubules (By similarity).|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton|
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Provided below are standard protocols that you may find useful for product applications.
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M, Cell 2006 Nov 127 (3): 635-48. PMID: 17081983
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