|Other Accession||NP_001362.2, 1769, 13417 (mouse), 207117 (rat)|
|Predicted||Human, Mouse, Rat, Rabbit, Dog|
|Calculated MW||514664 Da|
|Other Names||Dynein heavy chain 8, axonemal, Axonemal beta dynein heavy chain 8, Ciliary dynein heavy chain 8, DNAH8|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DNAH8 (aa1738-1749) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton, cilium axoneme|
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Human V-ATPase gene can protect or predispose the host to pulmonary tuberculosis. Capparelli R, Palumbo D, Iannaccone M, Iannelli D, Genes and immunity 2009 Oct 10 (7): 641-6. PMID: 19536151
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