|Application ||WB, E|
|Other Accession||NP_079374.2, 80168|
|Predicted||Pig, Dog, Cow|
|Calculated MW||38196 Da|
|Other Names||2-acylglycerol O-acyltransferase 2, 184.108.40.206, Acyl-CoA:monoacylglycerol acyltransferase 2, MGAT2, hMGAT2, Diacylglycerol O-acyltransferase candidate 5, hDC5, Diacylglycerol acyltransferase 2-like protein 5, Monoacylglycerol O-acyltransferase 2, MOGAT2, DC5, DGAT2L5|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MOGAT2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Highly expressed in liver, small intestine, colon, stomach and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
A predominant role of acyl-CoA:monoacylglycerol acyltransferase-2 in dietary fat absorption implicated by tissue distribution, subcellular localization, and up-regulation by high fat diet. Cao J, Hawkins E, Brozinick J, Liu X, Zhang H, Burn P, Shi Y, The Journal of biological chemistry 2004 Apr 279 (18): 18878-86. PMID: 14966132
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