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SOST Antibody (C-Term)

Peptide-affinity purified goat antibody

  • IHC - SOST Antibody (C-Term) AF3348a
    AF3348a (4 µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BQB4
Other Accession NP_079513.1, 50964, 74499 (mouse), 80722 (rat)
Reactivity Human
Predicted Mouse, Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 24031 Da
Additional Information
Gene ID 50964
Other Names Sclerostin, SOST
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSOST Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level)
Research Areas
Citations (0)

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The -9247 T/C polymorphism in the SOST upstream regulatory region that potentially affects C/EBPalpha and FOXA1 binding is associated with osteoporosis. Huang QY, Li GH, Kung AW, Bone 2009 Aug 45 (2): 289-94. PMID: 19371798

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$ 325.00
Cat# AF3348a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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