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SEPT4 (aa425-435) Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - SEPT4 (aa425-435) Antibody (internal region) AF3355a
    AF3355a (1 µg/ml) staining of Human Heart lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43236
Other Accession NP_004565.1, NP_536341.1, NP_001185642.1, 5414, 18952 (mouse)
Reactivity Human, Mouse
Predicted Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 55098 Da
Additional Information
Gene ID 5414
Other Names Septin-4, Apoptosis-related protein in the TGF-beta signaling pathway, ARTS, Bradeion beta, Brain protein H5, CE5B3 beta, Cell division control-related protein 2, hCDCREL-2, Cerebral protein 7, Peanut-like protein 2, SEPT4, ARTS, PNUTL2, SEP4
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSEPT4 (aa425-435) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEPT4
Synonyms ARTS, PNUTL2, SEP4
Function Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Note=In platelets, found in areas surrounding alpha-granules.
Tissue Location Widely expressed in adult and fetal tissues with highest expression in adult brain (at protein level), heart, liver and adrenal gland and fetal heart, kidney, liver and lung Also expressed in colorectal cancers and malignant melanomas Expressed in platelets.
Research Areas
Citations (0)

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This antibody is expected to recognize isoform 1 (NP_004565.1), 3 (NP_536341.1) and 4 (NP_001185642.1). Amino acid numbering in name refers to NP_004565.1 sequence.


Absence of annulus in human asthenozoospermia: case report. Lhuillier P, Rode B, Escalier D, Lorès P, Dirami T, Bienvenu T, Gacon G, Dulioust E, Touré A Human reproduction (Oxford, England) 2009 Jun 24 (6): 1296-303. PMID: 19221096

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$ 325.00
Cat# AF3355a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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