|Application ||WB, IHC, E|
|Other Accession||NP_002428.1, 4358, 17527 (mouse), 360463 (rat)|
|Predicted||Mouse, Rat, Dog, Cow|
|Calculated MW||19733 Da|
|Other Names||Protein Mpv17, MPV17|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MPV17 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in mitochondria homeostasis. May be involved in the metabolism of reactive oxygen species and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance.|
|Cellular Location||Mitochondrion inner membrane; Multi- pass membrane protein|
|Tissue Location||Ubiquitous. Expressed in pancreas, kidney, muscle, liver, lung, placenta, brain and heart|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
MPV17-associated hepatocerebral mitochondrial DNA depletion syndrome: new patients and novel mutations. El-Hattab AW, Li FY, Schmitt E, Zhang S, Craigen WJ, Wong LJ, Molecular genetics and metabolism 2010 Mar 99 (3): 300-8. PMID: 20074988
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