|Application ||WB, IHC, E|
|Other Accession||NP_002066.1, NP_067642.1, 2784, 59345, 60449 (rat)|
|Calculated MW||37221 Da|
|Other Names||Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3, Transducin beta chain 3, GNB3|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GNB3 & GNB4 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize GNB3 & GNB4 (GeneID: 2784, 59345; ProteinID: NP_002066.1; NP_067642.1).
Frequencies of genetic polymorphisms related to triptans metabolism in chronic migraine. Gentile G, Missori S, Borro M, Sebastianelli A, Simmaco M, Martelletti P, The journal of headache and pain 2010 Apr 11 (2): 151-6. PMID: 20213484
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