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SLAMF8 Antibody (C-Term)

Peptide-affinity purified goat antibody

     
  • WB - SLAMF8 Antibody (C-Term) AF3382a
    HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human SLAMF8 with C-terminal MYC tag probed with AF3382a (0.01ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with AF3382a (0.01ug/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9P0V8
Other Accession NP_064510.1, 56833
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Additional Information
Other Names SLAM family member 8, B-lymphocyte activator macrophage expressed, BCM-like membrane protein, CD353, SLAMF8, BLAME
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSLAMF8 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLAMF8
Synonyms BLAME
Function May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in lymph node, spleen, thymus and bone marrow. EMBL; AF146761; AAF67470.1; -; mRNA EMBL; AK074669; BAC11123.1; -; mRNA EMBL; AL590560; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC109194; AAI09195.1; -; mRNA CCDS; CCDS1188.1; -. [Q9P0V8-1] CCDS; CCDS81387.1; -. [Q9P0V8-2] RefSeq; NP_001317670.1; NM_001330741.1. [Q9P0V8-2] RefSeq; NP_064510.1; NM_020125.2. [Q9P0V8-1] UniGene; Hs.438683; - ProteinModelPortal; Q9P0V8; - BioGrid; 121206; 1 IntAct; Q9P0V8; 2 STRING; 9606.ENSP00000289707; - BioMuta; SLAMF8; - DMDM; 67461583; - PaxDb; Q9P0V8; - PeptideAtlas; Q9P0V8; - PRIDE; Q9P0V8; - ProteomicsDB; 83604; - ProteomicsDB; 83605; -. [Q9P0V8-2] Ensembl; ENST00000289707; ENSP00000289707; ENSG00000158714. [Q9P0V8-1] Ensembl; ENST00000368104; ENSP00000357084; ENSG00000158714. [Q9P0V8-2] GeneID; 56833; - KEGG; hsa:56833; - UCSC; uc001fue.5; human. [Q9P0V8-1] CTD; 56833; - DisGeNET; 56833; - EuPathDB; HostDB:ENSG00000158714.10; - GeneCards; SLAMF8; - HGNC; HGNC:21391; SLAMF8 HPA; HPA067601; - MIM; 606620; gene neXtProt; NX_Q9P0V8; - OpenTargets; ENSG00000158714; - PharmGKB; PA134983606; - eggNOG; ENOG410IVMT; Eukaryota eggNOG; ENOG410Y74Q; LUCA GeneTree; ENSGT00510000048737; - HOGENOM; HOG000133036; - HOVERGEN; HBG083118; - InParanoid; Q9P0V8; - KO; K16853; - OMA; NFSVLMV; - OrthoDB; EOG091G0GFI; - PhylomeDB; Q9P0V8; - TreeFam; TF334964; - GeneWiki; SLAMF8; - GenomeRNAi; 56833; - PRO; PR:Q9P0V8; - Proteomes; UP000005640; Chromosome 1 Bgee; ENSG00000158714; - CleanEx; HS_SLAMF8; - Genevisible; Q9P0V8; HS GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW Gene3D; 2.60.40.10; -; 2 InterPro; IPR007110; Ig-like_dom InterPro; IPR036179; Ig-like_dom_sf InterPro; IPR013783; Ig-like_fold SUPFAM; SSF48726; SSF48726; 2 PROSITE; PS50835; IG_LIKE; 1 1: Evidence at protein level; Alternative splicing; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Immunoglobulin domain; Membrane; Polymorphism; Reference proteome; Signal; Transmembrane; Transmembrane helix SIGNAL 1 22 CHAIN 23 285 SLAM family member 8 /FTId=PRO_0000014965 TOPO_DOM 23 233 Extracellular. TRANSMEM 234 254 Helical. TOPO_DOM 255 285 Cytoplasmic. DOMAIN 128 215 Ig-like C2-type CARBOHYD 85 85 N-linked (GlcNAc...) asparagine DISULFID 152 201 {ECO:0000255|PROSITE-ProRule:PRU00114} VAR_SEQ 14 122 Missing (in isoform 2). /FTId=VSP_013896 VARIANT 5 5 P -> T (in dbSNP:rs2494514) /FTId=VAR_049940 VARIANT 99 99 G -> S (in dbSNP:rs34687326) /FTId=VAR_049941 VARIANT 129 129 V -> M (in dbSNP:rs3795331) /FTId=VAR_049942 SEQUENCE 285 AA; 31670 MW; 1BA63F4F90739AB2 CRC64; MVMRPLWSLL LWEALLPITV TGAQVLSKVG GSVLLVAARP PGFQVREAIW RSLWPSEELL ATFFRGSLET LYHSRFLGRA QLHSNLSLEL GPLESGDSGN FSVLMVDTRG QPWTQTLQLK VYDAVPRPVV QVFIAVERDA QPSKTCQVFL SCWAPNISEI TYSWRRETTM DFGMEPHSLF TDGQVLSISL GPGDRDVAYS CIVSNPVSWD LATVTPWDSC HHEAAPGKAS YKDVLLVVVP VSLLLMLVTL FSAWHWCPCS GKKKKDVHAD RVGPETENPL VQDLP
Research Areas
Citations (0)

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References

New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M, Genes and immunity 2010 Apr 11 (3): 232-8. PMID: 20237496

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$ 335.00
Cat# AF3382a
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