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COPA Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - COPA Antibody (internal region) AF3390a
    AF3390a (0.5 µg/ml) staining of Human Prostate lysate (35 µg protein in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P53621
Other Accession NP_001091868.1, NP_004362.2, 1314, 12847 (mouse), 304978 (rat)
Reactivity Human
Predicted Mouse, Rat, Pig, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 138346 Da
Additional Information
Gene ID 1314
Other Names Coatomer subunit alpha, Alpha-coat protein, Alpha-COP, HEP-COP, HEPCOP, Xenin, Xenopsin-related peptide, Proxenin, COPA
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCOPA Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
Cellular Location Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it
Tissue Location Uniformly expressed in a wide range of adult and fetal tissues. Xenin is found in gastric, duodenal and jejunal mucosa. Circulates in the blood. Seems to be confined to specific endocrine cells
Research Areas
Citations (0)

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This antibody is expected to recognize both reported isoforms (NP_001091868.1; NP_004362.2).


Yip1A regulates the COPI-independent retrograde transport from the Golgi complex to the ER. Kano F, Yamauchi S, Yoshida Y, Watanabe-Takahashi M, Nishikawa K, Nakamura N, Murata M, Journal of cell science 2009 Jul 122 (Pt 13): 2218-27. PMID: 19509059

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$ 325.00
Cat# AF3390a
(40 western blots)
Availability: 7-10 days
Bulk Size
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