|Application ||WB, E|
|Other Accession||NP_003016.1, 6455|
|Calculated MW||41490 Da|
|Other Names||Endophilin-A2, EEN fusion partner of MLL, Endophilin-2, Extra eleven-nineteen leukemia fusion gene protein, EEN, SH3 domain protein 2B, SH3 domain-containing GRB2-like protein 1, SH3GL1, CNSA1, SH3D2B|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Endophilin-A2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).|
|Cellular Location||Cytoplasm. Early endosome membrane; Peripheral membrane protein Cell projection, podosome Note=Associated with postsynaptic endosomes in hippocampal neurons.|
|Tissue Location||Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Activation of EGF receptor endocytosis and ERK1/2 signaling by BPGAP1 requires direct interaction with EEN/endophilin II and a functional RhoGAP domain. Lua BL, Low BC, Journal of cell science 2005 Jun 118 (Pt 12): 2707-21. PMID: 15944398
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