|Application ||WB, E|
|Other Accession||NP_003016.1, 6455|
|Calculated MW||41490 Da|
|Other Names||Endophilin-A2, EEN fusion partner of MLL, Endophilin-2, Extra eleven-nineteen leukemia fusion gene protein, EEN, SH3 domain protein 2B, SH3 domain-containing GRB2-like protein 1, SH3GL1, CNSA1, SH3D2B|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Endophilin-A2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).|
|Cellular Location||Cytoplasm. Early endosome membrane; Peripheral membrane protein Cell projection, podosome Note=Associated with postsynaptic endosomes in hippocampal neurons.|
|Tissue Location||Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus|
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Provided below are standard protocols that you may find useful for product applications.
Activation of EGF receptor endocytosis and ERK1/2 signaling by BPGAP1 requires direct interaction with EEN/endophilin II and a functional RhoGAP domain. Lua BL, Low BC, Journal of cell science 2005 Jun 118 (Pt 12): 2707-21. PMID: 15944398
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