|Application ||WB, IHC, E|
|Other Accession||NP_000389.1, NP_001123291.1, NP_001165131.1, 1727|
|Calculated MW||34235 Da|
|Other Names||NADH-cytochrome b5 reductase 3, B5R, Cytochrome b5 reductase, 220.127.116.11, Diaphorase-1, NADH-cytochrome b5 reductase 3 membrane-bound form, NADH-cytochrome b5 reductase 3 soluble form, CYB5R3, DIA1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CYB5R3 / Dia 1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.|
|Cellular Location||Isoform 1: Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Mitochondrion outer membrane; Lipid-anchor; Cytoplasmic side|
|Tissue Location||Isoform 2 is expressed at late stages of erythroid maturation|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize all three reported isoforms (NP_000389.1; NP_001123291.1; NP_001165131.1).
RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1. Fernandez-Borja M, Janssen L, Verwoerd D, Hordijk P, Neefjes J, J. Cell. Sci. 2005 Jun 118 (Pt 12): 2661-70. PMID: 15944396
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