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IRF2BP2 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q7Z5L9 |
| Other Accession | NP_892017.2, NP_001070865.1, 359948, 270110 (mouse), 679357 (rat) |
| Predicted | Human, Mouse, Rat, Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 61025 Da |
| Gene ID | 359948 |
|---|---|
| Other Names | Interferon regulatory factor 2-binding protein 2, IRF-2-binding protein 2, IRF-2BP2, IRF2BP2 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | IRF2BP2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IRF2BP2 |
|---|---|
| Function | Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities (PubMed:12799427). Represses the NFAT1-dependent transactivation of NFAT-responsive promoters (PubMed:21576369). Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles (PubMed:20702774). Plays a role in immature B-cell differentiation (PubMed:27016798). |
| Cellular Location | Cytoplasm. Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize both reported isoforms (NP_892017.2; NP_001070865.1).
References
Identification of novel co-repressor molecules for Interferon Regulatory Factor-2. Childs KS, Goodbourn S, Nucleic acids research 2003 Jun 31 (12): 3016-26. PMID: 12799427
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