|Other Accession||NP_892017.2, NP_001070865.1, 359948, 270110 (mouse), 679357 (rat)|
|Predicted||Human, Mouse, Rat, Cow|
|Calculated MW||61025 Da|
|Other Names||Interferon regulatory factor 2-binding protein 2, IRF-2-binding protein 2, IRF-2BP2, IRF2BP2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IRF2BP2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscle.|
|Cellular Location||Cytoplasm. Nucleus.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_892017.2; NP_001070865.1).
Identification of novel co-repressor molecules for Interferon Regulatory Factor-2. Childs KS, Goodbourn S, Nucleic acids research 2003 Jun 31 (12): 3016-26. PMID: 12799427
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