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GNAQ / ALPHA-q (aa162-175) Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - GNAQ / ALPHA-q (aa162-175) Antibody (internal region) AF3471a
    AF3471a (0.1 µg/ml) staining of Peripheral Blood Lymphocytes lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • WB - GNAQ / ALPHA-q (aa162-175) Antibody (internal region) AF3471a
    AF3471a (0.1µg/ml) staining of Mouse (A) and Rat (B) Testis lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • WB - GNAQ / ALPHA-q (aa162-175) Antibody (internal region) AF3471a
    AF3471a (0.1µg/ml) staining of Pig Colon (A) and Pig Spleen (B) lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P50148
Other Accession NP_002063.2, 2776, 14682 (mouse), 81666 (rat)
Reactivity Human, Mouse, Rat
Predicted Pig, Cow, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 42142 Da
Additional Information
Gene ID 2776
Other Names Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein alpha-q, GNAQ, GAQ
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGNAQ / ALPHA-q (aa162-175) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GAQ
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).
Cellular Location Nucleus. Membrane. Nucleus membrane. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes.
Tissue Location Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level).
Research Areas
Citations (0)

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Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation. Ngai J, Inngjerdingen M, Berge T, Taskén K, BMC immunology 2009 10 : 27. PMID: 19426503

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$ 325.00
Cat# AF3471a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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