|Other Accession||NP_149030.2, 84667, 84653 (mouse), 305811 (rat)|
|Predicted||Human, Mouse, Rat, Pig, Cow|
|Calculated MW||24899 Da|
|Other Names||Transcription factor HES-7, hHes7, Class B basic helix-loop-helix protein 37, bHLHb37, Hairy and enhancer of split 7, bHLH factor Hes7, HES7, BHLHB37|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Hes7 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Two novel missense mutations in HAIRY-AND-ENHANCER-OF-SPLIT-7 in a family with spondylocostal dysostosis. Sparrow DB, Sillence D, Wouters MA, Turnpenny PD, Dunwoodie SL, European journal of human genetics : EJHG 2010 Jun 18 (6): 674-9. PMID: 20087400
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