|Other Accession||NP_149030.2, 84667, 84653 (mouse), 305811 (rat)|
|Predicted||Human, Mouse, Rat, Pig, Cow|
|Calculated MW||24899 Da|
|Other Names||Transcription factor HES-7, hHes7, Class B basic helix-loop-helix protein 37, bHLHb37, Hairy and enhancer of split 7, bHLH factor Hes7, HES7, BHLHB37|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Hes7 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Two novel missense mutations in HAIRY-AND-ENHANCER-OF-SPLIT-7 in a family with spondylocostal dysostosis. Sparrow DB, Sillence D, Wouters MA, Turnpenny PD, Dunwoodie SL, European journal of human genetics : EJHG 2010 Jun 18 (6): 674-9. PMID: 20087400
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