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NDR1 / STK38 Antibody (C-Term, near)

Peptide-affinity purified goat antibody

     
  • WB - NDR1 / STK38 Antibody (C-Term, near) AF3490a
    AF3490a (0.5 µg/ml) staining of Human Spleen lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q15208
Other Accession NP_009202.1, 11329, 361813 (rat)
Reactivity Human, Rat
Predicted Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 54190 Da
Additional Information
Gene ID 11329
Other Names Serine/threonine-protein kinase 38, 2.7.11.1, NDR1 protein kinase, Nuclear Dbf2-related kinase 1, STK38 {ECO:0000312|EMBL:AAH12085.1}
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNDR1 / STK38 Antibody (C-Term, near) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STK38 {ECO:0000312|EMBL:AAH12085.1}
Function Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2.
Cellular Location Nucleus. Cytoplasm.
Tissue Location Ubiquitously expressed with highest levels observed in peripheral blood leukocytes.
Research Areas
Citations (0)
citation

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Background

This antibody is NOT expected to cross-react with STK38L (GeneID 23012).

References

Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases. Kohler RS, Schmitz D, Cornils H, Hemmings BA, Hergovich A, Molecular and cellular biology 2010 Sep 30 (18): 4507-20. PMID: 20624913

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$ 341.00
Cat# AF3490a
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Availability: 7-10 days
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