Orexin Receptor 2 (aa405-419) Antibody (internal region, near C-Term)
Peptide-affinity purified goat antibody
|Application ||WB, E|
|Other Accession||NP_001517.2, 3062, 387285 (mouse), 25605 (rat)|
|Predicted||Human, Rat, Pig, Dog, Cow|
|Calculated MW||50694 Da|
|Other Names||Orexin receptor type 2, Ox-2-R, Ox2-R, Ox2R, Hypocretin receptor type 2, HCRTR2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Orexin Receptor 2 (aa405-419) Antibody (internal region, near C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).|
|Cellular Location||Cell membrane; Multi- pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Genomic organization and regulation of the human orexin (hypocretin) receptor 2 gene: identification of alternative promoters. Chen J, Randeva HS, The Biochemical journal 2010 May 427 (3): 377-90. PMID: 20156195
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