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LAMA5 (aa1029-1043) Antibody (internal region)

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
E
Primary Accession O15230
Other Accession NP_005551.3, 3911
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 399737 Da
Additional Information
Gene ID 3911
Other Names Laminin subunit alpha-5, Laminin-10 subunit alpha, Laminin-11 subunit alpha, Laminin-15 subunit alpha, LAMA5, KIAA0533, KIAA1907
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLAMA5 (aa1029-1043) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LAMA5
Synonyms KIAA0533, KIAA1907
Function Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Plays a role in the regulation of skeletogenesis, through a mechanism that involves integrin-mediated signaling and PTK2B/PYK2 (PubMed:33242826).
Cellular Location Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component
Tissue Location Expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta. Little or no expression in brain and liver. Expressed in muscle, ligaments, periosteum, trabecular bone and throughout the cartilage, particularly in the growth plate and in articular chondrocytes (PubMed:33242826)
Research Areas
Citations (0)
citation

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References

Association of a common LAMA5 variant with anthropometric and metabolic traits in an Italian cohort of healthy elderly subjects. De Luca M, Crocco P, Wiener H, Tiwari HK, Passarino G, Rose G. Exp Gerontol. 2011 Jan;46(1):60-4. PMID: 20951195

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$ 216.00
Cat# AF3522a
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