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PDIA2 (aa477-481) Antibody (internal region, near C-Term)

Peptide-affinity purified goat antibody

     
  • WB - PDIA2 (aa477-481) Antibody (internal region, near C-Term) AF3525a
    AF3525a (0.1 µg/ml) staining of Human (A), Mouse (B) and Rat (C) Pancreas lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
  • IHC - PDIA2 (aa477-481) Antibody (internal region, near C-Term) AF3525a
    AF3525a (3.8 µg/ml) staining of paraffin embedded Human Pancreas. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession Q13087
Other Accession NP_006840.2, 64714, 69191 (mouse), 287164 (rat)
Reactivity Human, Rat
Predicted Mouse
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 58206 Da
Additional Information
Gene ID 64714
Other Names Protein disulfide-isomerase A2, 5.3.4.1, Pancreas-specific protein disulfide isomerase, PDIp, PDIA2, PDIP
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPDIA2 (aa477-481) Antibody (internal region, near C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDIA2
Synonyms PDIP
Function Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.
Cellular Location Endoplasmic reticulum lumen {ECO:0000255|PROSITE- ProRule:PRU10138}
Tissue Location Highly expressed in pancreas (at protein level).
Research Areas
Citations (0)
citation

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References

Protein disulfide isomerase-immunopositive inclusions in patients with Alzheimer disease. Honjo Y, Ito H, Horibe T, Takahashi R, Kawakami K. Brain Res. 2010 Aug 19;1349:90-6. PMID: 20550946

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$ 341.00
Cat# AF3525a
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Availability: 7-10 days
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