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PTCH1 (aa266-280) Antibody (C or N-Term)

Peptide-affinity purified goat antibody

  • WB - PTCH1 (aa266-280) Antibody (C or N-Term) AF3530a
    AF3530a (2 µg/ml) staining of Mouse fetal Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13635
Other Accession NP_000255.2, NP_001077072.1, NP_001077071.1, NP_001077073.1, 5727, 19206 (mouse), 89830 (rat)
Reactivity Mouse
Predicted Human, Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 160545 Da
Additional Information
Gene ID 5727
Other Names Protein patched homolog 1, PTC, PTC1, PTCH1, PTCH
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTCH1 (aa266-280) Antibody (C or N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTCH1
Synonyms PTCH
Function Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location In the adult, expressed in brain, lung, liver, heart, placenta, skeletal muscle, pancreas and kidney. Expressed in tumor cells but not in normal skin
Research Areas
Citations (0)

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This antibody is expected to recognize all reported isoforms (NP_000255.2; NP_001077072.1; NP_001077071.1; NP_001077073.1). Reported variants represent identical protein: NP_001077075.1, NP_001077074.1, NP_001077073.1, NP_001077076.1


Detecting tissue-specific alternative splicing and disease-associated aberrant
splicing of the PTCH gene with exon junction microarrays. Nagao K, Togawa N, Fujii K, Uchikawa H, Kohno Y, Yamada M, Miyashita T. Hum Mol Genet. 2005 Nov 15;14(22):3379-88. PMID: 16203740

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$ 325.00
Cat# AF3530a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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