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AES Antibody (N-Term)

Peptide-affinity purified goat antibody

  • WB - AES Antibody (N-Term) AF3556a
    AF3556a (0.3 µg/ml) staining of Human Cerebral Cortex lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q08117
Other Accession NP_945320.1, NP_001121.2, NP_945321.1, 166, 14797 (mouse), 29466 (rat)
Reactivity Human
Predicted Mouse, Rat
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 21970 Da
Additional Information
Gene ID 166
Other Names Amino-terminal enhancer of split, Amino enhancer of split, Gp130-associated protein GAM, Grg-5, Groucho-related protein 5, Protein ESP1, Protein GRG, AES, GRG, GRG5
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAES Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AES
Synonyms GRG, GRG5
Function Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development.
Cellular Location Nucleus.
Tissue Location Found predominantly in muscle, heart and Placenta. In fetal tissues, abundantly expressed in the heart, lung, kidney, brain and liver
Research Areas
Citations (0)

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This antibody is expected to recognize all reported isoforms (NP_945320.1; NP_001121.2; NP_945321.1).


Histone deacetylase-related protein inhibits AES-mediated neuronal cell death by direct interaction. Zhang X, Chen HM, Jaramillo E, Wang L, D'Mello SR. J Neurosci Res. 2008 Aug 15;86(11):2423-31. PMID: 18438919

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$ 325.00
Cat# AF3556a
(40 western blots)
Availability: 7-10 days
Bulk Size
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