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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Goat Antibodies   >   KEAP1 (aa41-53) Antibody (internal region, near N-Term)   

KEAP1 (aa41-53) Antibody (internal region, near N-Term)

Peptide-affinity purified goat antibody

  • WB - KEAP1 (aa41-53) Antibody (internal region, near N-Term) AF3560a
    AF3560a (0.2 µg/ml) staining of NIH3T3 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • IHC - KEAP1 (aa41-53) Antibody (internal region, near N-Term) AF3560a
    AF3560a (3.8 µg/ml) staining of paraffin embedded Human Cerebellum. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14145
Other Accession NP_036421.2, 9817, 50868 (mouse), 117519 (rat)
Reactivity Human, Mouse
Predicted Rat, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 69666 Da
Additional Information
Gene ID 9817
Other Names Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, INrf2, Kelch-like protein 19, KEAP1, INRF2, KIAA0132, KLHL19
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKEAP1 (aa41-53) Antibody (internal region, near N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KEAP1
Synonyms INRF2, KIAA0132, KLHL19
Function Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Cellular Location Cytoplasm. Nucleus. Note=Shuttles between cytoplasm and nucleus
Tissue Location Broadly expressed, with highest levels in skeletal muscle.
Research Areas
Citations (0)

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Reported variants represent identical protein: NP_036421.2, NP_987096.1


An exceptionally potent inducer of cytoprotective enzymes: elucidation of the structural features that determine inducer potency and reactivity with Keap1. Dinkova-Kostova AT, Talalay P, Sharkey J, Zhang Y, Holtzclaw WD, Wang XJ, David E, Schiavoni KH, Finlayson S, Mierke DF, Honda T. J Biol Chem. 2010 Oct 29;285(44):33747-55. PMID: 20801881

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$ 325.00
Cat# AF3560a
(40 western blots)
Availability: 7-10 days
Bulk Size
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