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NRF2 (aa445-458) Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - NRF2 (aa445-458) Antibody (internal region) AF3595a
    AF3595a (0.3 µg/ml) staining of Human Lung lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16236
Other Accession NP_006155.2, NP_001138884.1, NP_001138885.1, 4780, 18024 (mouse), 83619 (rat)
Reactivity Human
Predicted Mouse, Rat, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 67827 Da
Additional Information
Gene ID 4780
Other Names Nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2, HEBP1, Nuclear factor, erythroid derived 2, like 2, NFE2L2, NRF2
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNRF2 (aa445-458) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NFE2L2
Synonyms NRF2
Function Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
Cellular Location Cytoplasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents
Tissue Location Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle
Research Areas
Citations (0)

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This antibody is expected to recognize all reported isoforms (NP_006155.2; NP_001138884.1; NP_001138885.1).


Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, Yamamoto M. Genes Dev. 1999 Jan 1;13(1):76-86. PMID: 9887101

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$ 325.00
Cat# AF3595a
(40 western blots)
Availability: 7-10 days
Bulk Size
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