|Application ||IHC, E|
|Other Accession||NP_000603.1, NP_001121070.1, 3481, 16002 (mouse), 24483 (rat)|
|Predicted||Mouse, Rat, Pig, Dog, Cow|
|Calculated MW||20140 Da|
|Other Names||Insulin-like growth factor II, IGF-II, Somatomedin-A, T3M-11-derived growth factor, Insulin-like growth factor II, Insulin-like growth factor II Ala-25 Del, Preptin, IGF2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IGF2 (aa81-93) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_000603.1; NP_001121070.1). Reported variants represent identical protein: NP_000603.1, NP_001007140.2
Long range interactions regulate Igf2 gene transcription during skeletal muscle differentiation. Alzhanov DT, McInerney SF, Rotwein P. J Biol Chem. 2010 Dec 10;285(50):38969-77. PMID: 20937833
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