cardiolipin synthase 1 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9UJA2 |
Other Accession | NP_061968.1, NP_001120930.1, 54675 |
Reactivity | Human |
Predicted | Mouse, Rat, Pig, Dog, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 32593 Da |
Gene ID | 54675 |
---|---|
Other Names | Cardiolipin synthase, CLS, 2.7.8.-, Protein GCD10 homolog, CRLS1, C20orf155, CLS1 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | cardiolipin synthase 1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CRLS1 |
---|---|
Synonyms | C20orf155, CLS1 |
Function | Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. |
Cellular Location | Mitochondrion inner membrane; Multi-pass membrane protein |
Tissue Location | Highly expressed in tissues such as heart, skeletal muscle and liver. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize both reported isoforms (NP_061968.1; NP_001120930.1).
References
Infections and the antiphospholipid syndrome. García-Carrasco M, Galarza-Maldonado C, Mendoza-Pinto C, Escarcega RO, Cervera R. Clin Rev Allergy Immunol. 2009 Jun;36(2-3):104-8. PMID: 19089659
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