|Application ||WB, E|
|Other Accession||NP_061968.1, NP_001120930.1, 54675|
|Predicted||Mouse, Rat, Pig, Dog, Cow|
|Calculated MW||32593 Da|
|Other Names||Cardiolipin synthase, CLS, 2.7.8.-, Protein GCD10 homolog, CRLS1, C20orf155, CLS1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||cardiolipin synthase 1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
|Tissue Location||Highly expressed in tissues such as heart, skeletal muscle and liver.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_061968.1; NP_001120930.1).
Infections and the antiphospholipid syndrome. García-Carrasco M, Galarza-Maldonado C, Mendoza-Pinto C, Escarcega RO, Cervera R. Clin Rev Allergy Immunol. 2009 Jun;36(2-3):104-8. PMID: 19089659
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