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cardiolipin synthase 1 Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - cardiolipin synthase 1 Antibody (internal region) AF3607a
    AF3607a (0.2 µg/ml) staining of HEK293 lysate (35 µg protein in RIPA buffer). Detected by chemiluminescence.
    detail
  • IHC - cardiolipin synthase 1 Antibody (internal region) AF3607a
    AF3607a (5 µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9UJA2
Other Accession NP_061968.1, NP_001120930.1, 54675
Reactivity Human
Predicted Mouse, Rat, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 32593 Da
Additional Information
Gene ID 54675
Other Names Cardiolipin synthase, CLS, 2.7.8.-, Protein GCD10 homolog, CRLS1, C20orf155, CLS1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautionscardiolipin synthase 1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRLS1
Synonyms C20orf155, CLS1
Function Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein
Tissue Location Highly expressed in tissues such as heart, skeletal muscle and liver.
Research Areas
Citations (0)
citation

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Background

This antibody is expected to recognize both reported isoforms (NP_061968.1; NP_001120930.1).

References

Infections and the antiphospholipid syndrome. García-Carrasco M, Galarza-Maldonado C, Mendoza-Pinto C, Escarcega RO, Cervera R. Clin Rev Allergy Immunol. 2009 Jun;36(2-3):104-8. PMID: 19089659

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$ 341.00
Cat# AF3607a
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